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Brief Description About Mesothelioma

by hasan on Jan.01, 2010, under Health

Brief Description About Mesothelioma Mesothelioma is a rare type of cancer that typically affects the lining of the lungs, heart and abdomen. This cancer occurs about four times more frequently in men than in women and all forms of mesothelioma, except for benign mesothelioma, are invariably fatal. Mesothelioma is an aggressive cancer that affects the mesothelium causing cells in the membrane to become cancerous and divide rapidly. This causes the thickening of the membrane, fluid buildup and the formation of tumors. This can result in difficulty breathing, nausea, fatigue and a myriad of other concerns.

What are the main causes of mesothelioma? Mesothelioma is most predominantly caused by asbestos exposure. Asbestos fibers that are inhaled through the mouth and nose may eventually become embedded in the lining of the lungs, causing damage and resulting in lung cancer or asbestosis (scar tissue formation in the lungs). It has also been found that swallowing asbestos fibers could contribute to a form of mesothelioma originating in the abdomen called peritoneal mesothelioma.

Mesothelioma generally results from occupational exposure but there are instances of environmental exposure to asbestos that can cause the disease. Oftentimes second hand exposure of a family member to an asbestos workers dirty work clothes can result in that family member developing mesothelioma.

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Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Diagnosis begins with a review of the patient’s medical history. A history of exposure to asbestos may increase clinical suspicion for mesothelioma. A physical examination is performed, followed by chest X-ray and often lung function tests. The X-ray may reveal pleural thickening commonly seen after asbestos exposure and increases suspicion of mesothelioma. A CT (or CAT) scan or an MRI is usually performed. If a large amount of fluid is present, abnormal cells may be detected by cytopathology if this fluid is aspirated with a syringe. For pleural fluid this is done by a pleural tap or chest drain, in ascites with an paracentesis or ascitic drain and in a pericardial effusion with pericardiocentesis. While absence of malignant cells on cytology does not completely exclude mesothelioma, it makes it much more unlikely, especially if an alternative diagnosis can be made (e.g. tuberculosis, heart failure).

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